Protein serine/threonine phosphatase PPEF-1 suppresses genotoxic stress response via dephosphorylation of PDCD5

Programmed cell death 5 (PDCD5) is believed to play a crucial role in p53 activation; however, the underlying mechanism of how PDCD5 function is regulated during apoptosis remains obscure. Here, we report that the serine/threonine phosphatase PPEF-1 interacts with and dephosphorylates PDCD5 at Ser-1...

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Detalles Bibliográficos
Autores principales: Park, Soo-Yeon, Seo, Jaesung, Choi, Hyo-Kyoung, Oh, Hye-Jeong, Guk, Garam, Lee, Yoo-Hyun, Lee, Jeongmin, Jun, Woo Jin, Choi, Kyung-Chul, Yoon, Ho-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209732/
https://www.ncbi.nlm.nih.gov/pubmed/28051100
http://dx.doi.org/10.1038/srep39222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209732/
https://www.ncbi.nlm.nih.gov/pubmed/28051100
http://dx.doi.org/10.1038/srep39222

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