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Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer’s Disease Model

The activity of the ubiquitin proteasome system (UPS) is downregulated in aggregation diseases such as Alzheimer’s disease (AD). In this study, we investigated the therapeutic potential of the Agouti-related peptide (AgRP), which is secreted by human mesenchymal stem cells (MSCs), in terms of its ef...

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Detalles Bibliográficos
Autores principales: Lee, Na Kyung, Park, Sang Eon, Kwon, Soo Jin, Shim, Sangmi, Byeon, Yeji, Kim, Jong-Hwa, Na, Duk L., Chang, Jong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209736/
https://www.ncbi.nlm.nih.gov/pubmed/28051110
http://dx.doi.org/10.1038/srep39340