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Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer’s Disease Model
The activity of the ubiquitin proteasome system (UPS) is downregulated in aggregation diseases such as Alzheimer’s disease (AD). In this study, we investigated the therapeutic potential of the Agouti-related peptide (AgRP), which is secreted by human mesenchymal stem cells (MSCs), in terms of its ef...
Autores principales: | Lee, Na Kyung, Park, Sang Eon, Kwon, Soo Jin, Shim, Sangmi, Byeon, Yeji, Kim, Jong-Hwa, Na, Duk L., Chang, Jong Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209736/ https://www.ncbi.nlm.nih.gov/pubmed/28051110 http://dx.doi.org/10.1038/srep39340 |
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