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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
BACKGROUND: Betulinic acid and betulin are triterpenes that have anticancer properties in various types of cancer. Unfortunately, the bioavailability and the bio-distribution of betulinic acid and its metabolic precursor, betulin are very low because of poor solubility in aqueous buffers. METHODS: I...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209806/ https://www.ncbi.nlm.nih.gov/pubmed/28053599 http://dx.doi.org/10.1186/s12935-016-0369-3 |