Chromosomal position effect influences the heterologous expression of genes and biosynthetic gene clusters in Streptomyces albus J1074

BACKGROUND: Efforts to construct the Streptomyces host strain with enhanced yields of heterologous product have focussed mostly on engineering of primary metabolism and/or the deletion of endogenous biosynthetic gene clusters. However, other factors, such as chromosome compactization, have been show...

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Detalles Bibliográficos
Autores principales: Bilyk, Bohdan, Horbal, Liliya, Luzhetskyy, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209838/
https://www.ncbi.nlm.nih.gov/pubmed/28052753
http://dx.doi.org/10.1186/s12934-016-0619-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209838/
https://www.ncbi.nlm.nih.gov/pubmed/28052753
http://dx.doi.org/10.1186/s12934-016-0619-z

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