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Vincristine alleviates adriamycin-induced nephropathy through stabilizing actin cytoskeleton

Antimicrotubule agent vincristine (VCR) has long been known as an alternative treatment for frequent relapse nephrotic syndrome and steroid-dependent nephrotic syndrome (SDNS). However, the mechanism is unknown. Here we found that VCR at a dosage much lower than that as an antimicrotubule agent can...

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Detalles Bibliográficos
Autores principales: Yin, Lei, Mao, Youying, Song, Hejie, Wang, Ye, Zhou, Wei, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209879/
https://www.ncbi.nlm.nih.gov/pubmed/28053698
http://dx.doi.org/10.1186/s13578-016-0129-z