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Neural hyperactivity in the amygdala induced by chronic treatment of rats with analgesics may elucidate the mechanisms underlying psychiatric comorbidities associated with medication-overuse headache

BACKGROUND: Patients with medication-overuse headache suffer not only from chronic headache, but often from psychiatric comorbidities, such as anxiety and depression. The mechanisms underlying these comorbidities are unclear, but the amygdala is likely to be involved in their pathogenesis. To invest...

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Detalles Bibliográficos
Autores principales: Wanasuntronwong, Aree, Jansri, Ukkrit, Srikiatkhachorn, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209916/
https://www.ncbi.nlm.nih.gov/pubmed/28049513
http://dx.doi.org/10.1186/s12868-016-0326-z