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Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2
The liver has an intrinsic capacity to regenerate in response to injury or surgical resection. Nevertheless, circumstances in which hepatocytes are unresponsive to proliferative signals result in impaired regeneration and hepatic failure. As the Hippo pathway has a canonical role in the maintenance...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210079/ https://www.ncbi.nlm.nih.gov/pubmed/27940445 http://dx.doi.org/10.15252/emmm.201506089 |