Irisin Lowers Blood Pressure by Improvement of Endothelial Dysfunction via AMPK‐Akt‐eNOS‐NO Pathway in the Spontaneously Hypertensive Rat

BACKGROUND: Exercise is a major nonpharmacological treatment for hypertension, but its underlying mechanisms are still not completely elucidated. Irisin, a polypeptide containing 112 amino acids, which is secreted mainly by skeletal muscle cells during exercise, exerts a protective role in metabolic...

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Detalles Bibliográficos
Autores principales: Fu, Jinjuan, Han, Yu, Wang, Jialiang, Liu, Yukai, Zheng, Shuo, Zhou, Lin, Jose, Pedro A., Zeng, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210324/
https://www.ncbi.nlm.nih.gov/pubmed/27912206
http://dx.doi.org/10.1161/JAHA.116.003433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210324/
https://www.ncbi.nlm.nih.gov/pubmed/27912206
http://dx.doi.org/10.1161/JAHA.116.003433

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