Knockdown of Inhibitory Guanine Nucleotide Binding Protein Giα‐2 by Antisense Oligodeoxynucleotides Attenuates the Development of Hypertension and Tachycardia in Spontaneously Hypertensive Rats

BACKGROUND: We previously showed that the levels of both Giα‐2 and Giα‐3 proteins were augmented in spontaneously hypertensive rats (SHRs) before the onset of hypertension. In addition, intraperitoneal injection of pertussis toxin, which inactivates both Giα proteins, prevented the development of hy...

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Detalles Bibliográficos
Autores principales: Ali El‐Basyuni, Yousra, Li, Yuan, Anand‐Srivastava, Madhu B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210347/
https://www.ncbi.nlm.nih.gov/pubmed/27912212
http://dx.doi.org/10.1161/JAHA.116.004594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210347/
https://www.ncbi.nlm.nih.gov/pubmed/27912212
http://dx.doi.org/10.1161/JAHA.116.004594

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