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Neuronal Na(v)1.8 Channels as a Novel Therapeutic Target of Acute Atrial Fibrillation Prevention

BACKGROUND: Ganglionated plexus have been developed as additional ablation targets to improve the outcome of atrial fibrillation (AF) besides pulmonary vein isolation. Recent studies implicated an intimate relationship between neuronal sodium channel Na(v)1.8 (encoded by SCN10A) and AF. The underlyi...

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Detalles Bibliográficos
Autores principales: Chen, XiaoMeng, Yu, LiLei, Shi, ShaoBo, Jiang, Hong, Huang, CongXin, Desai, Mayurika, Li, YiGang, Barajas‐Martinez, Hector, Hu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210368/
https://www.ncbi.nlm.nih.gov/pubmed/27806967
http://dx.doi.org/10.1161/JAHA.116.004050