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Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models

Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes of hypoxia, and other undetermined causes, PH...

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Detalles Bibliográficos
Autores principales: Ahmed, Mohamed, VanPatten, Sonya, Lakshminrusimha, Satyan, Patel, Hardik, Coleman, Thomas R., Al‐Abed, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210380/
https://www.ncbi.nlm.nih.gov/pubmed/28039410
http://dx.doi.org/10.14814/phy2.13069