Loss of Caspase‐Activated DNase Protects Against Atherosclerosis in Apolipoprotein E–Deficient Mice

BACKGROUND: Atherosclerosis is a chronic disease that is closely related to inflammation and macrophage apoptosis, which leads to secondary necrosis and proinflammatory responses in advanced lesions. Caspase‐activated DNase (CAD) is a double‐strand specific endonuclease that leads to the subsequent...

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Detalles Bibliográficos
Autores principales: Chao, Meng‐Lin, Guo, Junhong, Cheng, Wen‐Lin, Zhu, Xue‐Yong, She, Zhi‐Gang, Huang, Zan, Ji, Yong, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210397/
https://www.ncbi.nlm.nih.gov/pubmed/28007744
http://dx.doi.org/10.1161/JAHA.116.004362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210397/
https://www.ncbi.nlm.nih.gov/pubmed/28007744
http://dx.doi.org/10.1161/JAHA.116.004362

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