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Loss of Caspase‐Activated DNase Protects Against Atherosclerosis in Apolipoprotein E–Deficient Mice
BACKGROUND: Atherosclerosis is a chronic disease that is closely related to inflammation and macrophage apoptosis, which leads to secondary necrosis and proinflammatory responses in advanced lesions. Caspase‐activated DNase (CAD) is a double‐strand specific endonuclease that leads to the subsequent...
Autores principales: | Chao, Meng‐Lin, Guo, Junhong, Cheng, Wen‐Lin, Zhu, Xue‐Yong, She, Zhi‐Gang, Huang, Zan, Ji, Yong, Li, Hongliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210397/ https://www.ncbi.nlm.nih.gov/pubmed/28007744 http://dx.doi.org/10.1161/JAHA.116.004362 |
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