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Effects of cell-cycle-dependent expression on random fluctuations in protein levels

Expression of many genes varies as a cell transitions through different cell-cycle stages. How coupling between stochastic expression and cell cycle impacts cell-to-cell variability (noise) in the level of protein is not well understood. We analyse a model where a stable protein is synthesized in ra...

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Detalles Bibliográficos
Autores principales: Soltani, Mohammad, Singh, Abhyudai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210684/
https://www.ncbi.nlm.nih.gov/pubmed/28083102
http://dx.doi.org/10.1098/rsos.160578