Sensitivity to Oxidative Stress in DJ-1-Deficient Dopamine Neurons: An ES- Derived Cell Model of Primary Parkinsonism

The hallmark of Parkinson's disease (PD) is the selective loss of dopamine neurons in the ventral midbrain. Although the cause of neurodegeneration in PD is unknown, a Mendelian inheritance pattern is observed in rare cases, indicating a genetic factor. Furthermore, pathological analyses of PD...

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Detalles Bibliográficos
Autores principales: Martinat, Cecile, Shendelman, Shoshana, Jonason, Alan, Leete, Thomas, Beal, M. Flint, Yang, Lichuan, Floss, Thomas, Abeliovich, Asa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC521171/
https://www.ncbi.nlm.nih.gov/pubmed/15502868
http://dx.doi.org/10.1371/journal.pbio.0020327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC521171/
https://www.ncbi.nlm.nih.gov/pubmed/15502868
http://dx.doi.org/10.1371/journal.pbio.0020327

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