Characterization of the Plasmodium falciparum and P. berghei glycerol 3‐phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast

Malaria parasites can synthesize fatty acids via a type II fatty acid synthesis (FASII) pathway located in their apicoplast. The FASII pathway has been pursued as an anti‐malarial drug target, but surprisingly little is known about its role in lipid metabolism. Here we characterize the apicoplast gl...

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Detalles Bibliográficos
Autores principales: Shears, Melanie J., MacRae, James I., Mollard, Vanessa, Goodman, Christopher D., Sturm, Angelika, Orchard, Lindsey M., Llinás, Manuel, McConville, Malcolm J., Botté, Cyrille Y., McFadden, Geoffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213128/
https://www.ncbi.nlm.nih.gov/pubmed/27324409
http://dx.doi.org/10.1111/cmi.12633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213128/
https://www.ncbi.nlm.nih.gov/pubmed/27324409
http://dx.doi.org/10.1111/cmi.12633

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