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Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease

PURPOSE OF REVIEW: APOE4 genotype is the strongest genetic risk factor for Alzheimer's disease. Prevailing evidence suggests that amyloid β plays a critical role in Alzheimer's disease. The objective of this article is to review the recent findings about the metabolism of apolipoprotein E...

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Detalles Bibliográficos
Autores principales: Liao, Fan, Yoon, Hyejin, Kim, Jungsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5213812/
https://www.ncbi.nlm.nih.gov/pubmed/27922847
http://dx.doi.org/10.1097/MOL.0000000000000383