Role of the BrafV637E mutation in hepatocarcinogenesis induced by treatment with diethylnitrosamine in neonatal B6C3F1 mice

The BrafV637E mutation is frequently reported in mouse hepatic tumors, depending on the mouse strain, and corresponds to the human BrafV600E mutation. In this study, we detected the BrafV637E mutation by whole‐exome analysis in 4/4 hepatic tumors induced by neonatal treatment with diethylnitrosamine...

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Detalles Bibliográficos
Autores principales: Yamamoto, Masahiro, Tanaka, Hiroki, Xin, Bing, Nishikawa, Yuji, Yamazaki, Kosuke, Shimizu, Keiko, Ogawa, Katsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214095/
https://www.ncbi.nlm.nih.gov/pubmed/27253992
http://dx.doi.org/10.1002/mc.22510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214095/
https://www.ncbi.nlm.nih.gov/pubmed/27253992
http://dx.doi.org/10.1002/mc.22510

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