d‐ Versus l‐Glucose Conjugation: Mitochondrial Targeting of a Light‐Activated Dual‐Mode‐of‐Action Ruthenium‐Based Anticancer Prodrug

Light‐activated ruthenium polypyridyl anticancer prodrugs often suffer from poor water solubility, poor selectivity, and/or ill‐defined intracellular targets. Coordination of the d‐ or l‐glucose thioether ligand 3 (2‐(2‐(2‐(methylthio)ethoxy)ethoxy)ethyl‐β‐glucopyranoside) to the highly lipophilic r...

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Detalles Bibliográficos
Autores principales: Lameijer, Lucien N., Hopkins, Samantha L., Brevé, Tobias G., Askes, Sven H. C., Bonnet, Sylvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214309/
https://www.ncbi.nlm.nih.gov/pubmed/27859843
http://dx.doi.org/10.1002/chem.201603066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214309/
https://www.ncbi.nlm.nih.gov/pubmed/27859843
http://dx.doi.org/10.1002/chem.201603066

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