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Structural Analysis of G-Quadruplex Formation at the Human MEST Promoter

The promoter region of the imprinted gene MEST contains several motifs capable of forming G-quadruplex (G4) structures, which appear to contribute to consistent allelic dropout during polymerase chain reaction (PCR) analysis of this region. Here, we extend our previous analysis of MEST G4 structures...

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Detalles Bibliográficos
Autores principales: Stevens, Aaron J., Kennedy, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214457/
https://www.ncbi.nlm.nih.gov/pubmed/28052120
http://dx.doi.org/10.1371/journal.pone.0169433