Aminophylline suppresses stress-induced visceral hypersensitivity and defecation in irritable bowel syndrome

Pharmacological therapy for irritable bowel syndrome (IBS) has not been established. In order to find candidate drugs for IBS with diarrhea (IBS-D), we screened a compound library of drugs clinically used for their ability to prevent stress-induced defecation and visceral hypersensitivity in rats. W...

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Detalles Bibliográficos
Autores principales: Asano, Teita, Tanaka, Ken-ichiro, Tada, Arisa, Shimamura, Hikaru, Tanaka, Rikako, Maruoka, Hiroki, Takenaga, Mitsuko, Mizushima, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214462/
https://www.ncbi.nlm.nih.gov/pubmed/28054654
http://dx.doi.org/10.1038/srep40214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214462/
https://www.ncbi.nlm.nih.gov/pubmed/28054654
http://dx.doi.org/10.1038/srep40214

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