Cargando…

Aminophylline suppresses stress-induced visceral hypersensitivity and defecation in irritable bowel syndrome

Pharmacological therapy for irritable bowel syndrome (IBS) has not been established. In order to find candidate drugs for IBS with diarrhea (IBS-D), we screened a compound library of drugs clinically used for their ability to prevent stress-induced defecation and visceral hypersensitivity in rats. W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asano, Teita, Tanaka, Ken-ichiro, Tada, Arisa, Shimamura, Hikaru, Tanaka, Rikako, Maruoka, Hiroki, Takenaga, Mitsuko, Mizushima, Tohru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214462/ https://www.ncbi.nlm.nih.gov/pubmed/28054654 http://dx.doi.org/10.1038/srep40214

Ejemplares similares

Adenosine A(2B) Receptors: An Optional Target for the Management of Irritable Bowel Syndrome with Diarrhea?
por: Asano, Teita, et al.
Publicado: (2017)

A(2B) adenosine receptor inhibition by the dihydropyridine calcium channel blocker nifedipine involves colonic fluid secretion
por: Asano, Teita, et al.
Publicado: (2020)

Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity
por: Tanaka, Ken-Ichiro, et al.
Publicado: (2018)

Aldioxa improves delayed gastric emptying and impaired gastric compliance, pathophysiologic mechanisms of functional dyspepsia
por: Asano, Teita, et al.
Publicado: (2015)

Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity
por: Sugizaki, Toshifumi, et al.
Publicado: (2019)

Main ion channels and receptors associated with visceral hypersensitivity in irritable bowel syndrome
por: de Carvalho Rocha, Heraldo Arcela, et al.
Publicado: (2014)

New Pathways, New Targets: Visceral Hypersensitivity Pathogenesis in Irritable Bowel Syndrome
por: Barshop, Kenneth, et al.
Publicado: (2016)

The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments
por: Farzaei, Mohammad H, et al.
Publicado: (2016)

Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases
por: Ceuleers, Hannah, et al.
Publicado: (2016)

Piezo2: A Candidate Biomarker for Visceral Hypersensitivity in Irritable Bowel Syndrome?
por: Bai, Tao, et al.
Publicado: (2017)

The Importance of Visceral Hypersensitivity in Irritable Bowel Syndrome—Plant Metabolites in IBS Treatment
por: Dudzińska, Ewa, et al.
Publicado: (2023)

Global research progress of visceral hypersensitivity and irritable bowel syndrome: bibliometrics and visualized analysis
por: Tian, Siyu, et al.
Publicado: (2023)

The efficacy and neural mechanism of acupuncture therapy in the treatment of visceral hypersensitivity in irritable bowel syndrome
por: Yang, Yuanzhen, et al.
Publicado: (2023)

Superiority of pulmonary administration of mepenzolate bromide over other routes as treatment for chronic obstructive pulmonary disease
por: Tanaka, Ken-Ichiro, et al.
Publicado: (2014)

Allergy to the ethylenediamine component of aminophylline.
por: Toal, M., et al.
Publicado: (1992)

Comparison of Electroacupuncture and Moxibustion for Relieving Visceral Hypersensitivity in Rats with Constipation-Predominant Irritable Bowel Syndrome
por: Zhao, Ji-Meng, et al.
Publicado: (2016)

Role of hippocampal circKcnk9 in visceral hypersensitivity and anxiety comorbidity of irritable bowel syndrome
por: Liu, Yuan, et al.
Publicado: (2022)

The Effect of Topical Aminophylline on Hyposmia and Anosmia
por: Jahandideh, Hesam, et al.
Publicado: (2022)

Enhanced Antitumor Activity and Reduced Toxicity of 1,3‐Bis(2‐chloroethyl)‐1‐nitrosourea Administered in Lipid Microspheres to Tumor‐bearing Mice
por: Takenaga, Mitsuko, et al.
Publicado: (1993)

P2Y1R is involved in visceral hypersensitivity in rats with experimental irritable bowel syndrome
por: Wu, Jie, et al.
Publicado: (2017)

Comparison of the analgesic effects between electro-acupuncture and moxibustion with visceral hypersensitivity rats in irritable bowel syndrome
por: Zhao, Ji-Meng, et al.
Publicado: (2017)

Analysis of autonomic function during natural defecation in patients with irritable bowel syndrome using real-time recording with a wearable device
por: Nakata, Rieko, et al.
Publicado: (2022)

Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms
por: Botschuijver, Sara, et al.
Publicado: (2019)

5-HT(7) receptor-dependent intestinal neurite outgrowth contributes to visceral hypersensitivity in irritable bowel syndrome
por: Chang, Wen-Ying, et al.
Publicado: (2022)

Effects of Massa Medicata Fermentata on the intestinal pathogenic flagella bacteria and visceral hypersensitivity in rats with irritable bowel syndrome
por: Zhuang, Zhaomeng, et al.
Publicado: (2022)

The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
por: Barzegarnezhad, Ayyoub, et al.
Publicado: (2012)

Antidepressant Effect of Aminophylline After Ethanol Exposure
por: Escudeiro, Sarah Souza, et al.
Publicado: (2013)

Fructo-oligosaccharide intensifies visceral hypersensitivity and intestinal inflammation in a stress-induced irritable bowel syndrome mouse model
por: Chen, Bin-Rui, et al.
Publicado: (2017)

Increased expression of brain-derived neurotrophic factor is correlated with visceral hypersensitivity in patients with diarrhea-predominant irritable bowel syndrome
por: Zhang, Yu, et al.
Publicado: (2019)

Bifidobacterium longum alleviates irritable bowel syndrome-related visceral hypersensitivity and microbiota dysbiosis via Paneth cell regulation
por: Zhou, Chunhua, et al.
Publicado: (2020)

Potential Activity of the Purine Compounds Caffeine and Aminophylline on Bacteria
por: AL-Janabi, Ali Abdul Hussein S
Publicado: (2011)

Effects of hydrocortisone and aminophylline on the aggregation of equine platelets in vitro
por: Casella, Stefania, et al.
Publicado: (2011)

The influence of aminophylline on the nanostructure and nanomechanics of T lymphocytes: an AFM study
por: Huang, Xun, et al.
Publicado: (2014)

Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia
por: Schroeder, Thies, et al.
Publicado: (2017)

Aminophylline/benralizumab: Lack of efficacy and eosinopenia: case report
Publicado: (2022)

What Is the Therapeutic Mechanism of the Probiotics in Irritable Bowel Syndrome Patients With Visceral Hypersensitivity?: (Neurogastroenterol Motil 2014;26:705–714)
por: Kim, Ji Won
Publicado: (2014)

PDIA3 gene induces visceral hypersensitivity in rats with irritable bowel syndrome through the dendritic cell-mediated activation of T cells
por: Zhuang, Zhaomeng, et al.
Publicado: (2016)

Electroacupuncture Relieves Visceral Hypersensitivity by Inactivating Protease-Activated Receptor 2 in a Rat Model of Postinfectious Irritable Bowel Syndrome
por: Xu, Wanli, et al.
Publicado: (2018)

Effect of the interleukin 10 polymorphisms on interleukin 10 production and visceral hypersensitivity in Chinese patients with diarrhea-predominant irritable bowel syndrome
por: Zhu, Shi-Wei, et al.
Publicado: (2019)

Altered profiles of fecal metabolites correlate with visceral hypersensitivity and may contribute to symptom severity of diarrhea-predominant irritable bowel syndrome
por: Zhang, Wen-Xue, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5j8vofumq7t1djhsmd6e1gmual