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Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia

Common variable immunodeficiency (CVID) is a heterogeneous group of diseases. Our aim was to define sub-groups of CVID patients with similar phenotypes and clinical characteristics. Using eight-color flow cytometry, we analyzed both B- and T-cell phenotypes in a cohort of 88 CVID patients and 48 hea...

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Detalles Bibliográficos
Autores principales: Stuchlý, Jan, Kanderová, Veronika, Vlková, Marcela, Heřmanová, Ivana, Slámová, Lucie, Pelák, Ondřej, Taraldsrud, Eli, Jílek, Dalibor, Králíčková, Pavlína, Fevang, Børre, Trková, Marie, Hrušák, Ondřej, Froňková, Eva, Šedivá, Anna, Litzman, Jiří, Kalina, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214528/
https://www.ncbi.nlm.nih.gov/pubmed/28054583
http://dx.doi.org/10.1038/srep39710