Sam68/KHDRBS1-dependent NF-κB activation confers radioprotection to the colon epithelium in γ-irradiated mice

Previously we reported that Src-associated-substrate-during-mitosis-of-68kDa (Sam68/KHDRBS1) is pivotal for DNA damage-stimulated NF-κB transactivation of anti-apoptotic genes (Fu et al., 2016). Here we show that Sam68 is critical for genotoxic stress-induced NF-κB activation in the γ-irradiated col...

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Detalles Bibliográficos
Autores principales: Fu, Kai, Sun, Xin, Wier, Eric M, Hodgson, Andrea, Hobbs, Ryan P, Wan, Fengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214542/
https://www.ncbi.nlm.nih.gov/pubmed/27996939
http://dx.doi.org/10.7554/eLife.21957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214542/
https://www.ncbi.nlm.nih.gov/pubmed/27996939
http://dx.doi.org/10.7554/eLife.21957

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