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Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

Nuclear lamins are the major components of the nuclear lamina at the periphery of the nucleus, supporting the nuclear envelope and participating in many nuclear processes, including DNA replication, transcription and chromatin organization. A group of diseases, the laminopathies, is associated with...

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Detalles Bibliográficos
Autores principales: Wu, Di, Yates, Phillip A., Zhang, Haoyue, Cao, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214577/
https://www.ncbi.nlm.nih.gov/pubmed/27929926
http://dx.doi.org/10.1080/19491034.2016.1260803