The Potassium Channel KCa3.1 Represents a Valid Pharmacological Target for Astrogliosis-Induced Neuronal Impairment in a Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive decline of cognitive function. Astrogliosis plays a critical role in AD by instigating neuroinflammation, which leads ultimately to cognition decline. We previously showed that the intermediate-conductance Ca(2+)-a...

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Detalles Bibliográficos
Autores principales: Wei, Tianjiao, Yi, Mengni, Gu, Wen, Hou, Lina, Lu, Qin, Yu, Zhihua, Chen, Hongzhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214707/
https://www.ncbi.nlm.nih.gov/pubmed/28105015
http://dx.doi.org/10.3389/fphar.2016.00528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214707/
https://www.ncbi.nlm.nih.gov/pubmed/28105015
http://dx.doi.org/10.3389/fphar.2016.00528

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