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CAR-T cell therapy in gastrointestinal tumors and hepatic carcinoma: From bench to bedside
The chimeric antigen receptor (CAR) is a genetically engineered receptor that combines a scFv domain, which specifically recognizes the tumor-specific antigen, with T cell activation domains. CAR-T cell therapies have demonstrated tremendous efficacy against hematologic malignancies in many clinical...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214859/ https://www.ncbi.nlm.nih.gov/pubmed/28123893 http://dx.doi.org/10.1080/2162402X.2016.1251539 |