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Acepromazine inhibits hERG potassium ion channels expressed in human embryonic kidney 293 cells

The effects of acepromazine on human ether-à-go-go-related gene (hERG) potassium channels were investigated using whole-cell voltage-clamp technique in human embryonic kidney (HEK293) cells transfected with hERG. The hERG currents were recorded with or without acepromazine, and the steady-state and...

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Detalles Bibliográficos
Autores principales: Joo, Young Shin, Lee, Hong Joon, Choi, Jin-Sung, Sung, Ki-Wug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214913/
https://www.ncbi.nlm.nih.gov/pubmed/28066143
http://dx.doi.org/10.4196/kjpp.2017.21.1.75