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Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice
Advanced age is one of the risk factors for vascular diseases that are mainly caused by impaired nitric oxide (NO) production. It has been demonstrated that endothelial arginase constrains the activity of endothelial nitric oxide synthase (eNOS) and limits NO generation. Hence, arginase inhibition i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214914/ https://www.ncbi.nlm.nih.gov/pubmed/28066144 http://dx.doi.org/10.4196/kjpp.2017.21.1.83 |