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Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice

Advanced age is one of the risk factors for vascular diseases that are mainly caused by impaired nitric oxide (NO) production. It has been demonstrated that endothelial arginase constrains the activity of endothelial nitric oxide synthase (eNOS) and limits NO generation. Hence, arginase inhibition i...

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Detalles Bibliográficos
Autores principales: Nguyen, Minh Cong, Ryoo, Sungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214914/
https://www.ncbi.nlm.nih.gov/pubmed/28066144
http://dx.doi.org/10.4196/kjpp.2017.21.1.83

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