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High fat diet confers vascular hyper-contractility against angiotensin II through upregulation of MLCK and CPI-17
Obesity is a critical risk factor for the hypertension. Although angiotensin II (Ang II) in obese individuals is known to be upregulated in obesity-induced hypertension, direct evidence that explains the underlying mechanism for increased vascular tone and consequent increase in blood pressure (BP)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Physiological Society and The Korean Society of Pharmacology
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214916/ https://www.ncbi.nlm.nih.gov/pubmed/28066146 http://dx.doi.org/10.4196/kjpp.2017.21.1.99 |