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Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals
Inflammation is the host response to microbial infection or sterile injury that aims to eliminate the insult, repair the tissue and restore homeostasis. Macrophages and the NLRP3 inflammasome are key sentinels for both types of insult. Although it is well established that the NLRP3 inflammasome is a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214936/ https://www.ncbi.nlm.nih.gov/pubmed/26996064 http://dx.doi.org/10.1038/cmi.2016.11 |