The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

Inflammasomes are important for maintaining intestinal homeostasis, and dysbiosis contributes to the pathology of inflammatory bowel disease (IBD) and increases the risk for colorectal cancer. Inflammasome defects contribute to chronic intestinal inflammation and increase the susceptibility to colit...

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Detalles Bibliográficos
Autores principales: Ratsimandresy, Rojo A, Indramohan, Mohanalaxmi, Dorfleutner, Andrea, Stehlik, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214942/
https://www.ncbi.nlm.nih.gov/pubmed/27524110
http://dx.doi.org/10.1038/cmi.2016.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214942/
https://www.ncbi.nlm.nih.gov/pubmed/27524110
http://dx.doi.org/10.1038/cmi.2016.35

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