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Viral evasion of DNA-stimulated innate immune responses

Cellular sensing of virus-derived nucleic acids is essential for early defenses against virus infections. In recent years, the discovery of DNA sensing proteins, including cyclic GMP–AMP synthase (cGAS) and gamma-interferon-inducible protein (IFI16), has led to understanding of how cells evoke stron...

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Detalles Bibliográficos
Autores principales: Christensen, Maria H, Paludan, Søren R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214947/
https://www.ncbi.nlm.nih.gov/pubmed/26972769
http://dx.doi.org/10.1038/cmi.2016.06