Cargando…

Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade

Removal of immuno-suppression has been reported to enhance antitumor immunity primed by checkpoint inhibitors. Although PD-1 blockade failed to control tumor growth in a transgenic murine neuroblastoma model, concurrent inhibition of colony stimulating factor 1 receptor (CSF-1R) by BLZ945 reprogramm...

Descripción completa

Detalles Bibliográficos
Autores principales: Eissler, Nina, Mao, Yumeng, Brodin, David, Reuterswärd, Philippa, Andersson Svahn, Helene, Johnsen, John Inge, Kiessling, Rolf, Kogner, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214950/
https://www.ncbi.nlm.nih.gov/pubmed/28123870
http://dx.doi.org/10.1080/2162402X.2016.1232222