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Maintenance of the EBV-specific CD8(+) TCRαβ repertoire in immunosuppressed lung transplant recipients

Epstein-Barr virus (EBV) is one of the most common viruses in humans, capable of causing life-threatening infections and cancers in immunocompromised individuals. Although CD8(+) T cells provide key protection against EBV, the persistence and dynamics of specific T-cell receptor (TCR) clones during...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi HO, Bird, Nicola L, Grant, Emma J, Miles, John J, Thomas, Paul G, Kotsimbos, Tom C, Mifsud, Nicole A, Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214975/
https://www.ncbi.nlm.nih.gov/pubmed/27507557
http://dx.doi.org/10.1038/icb.2016.71