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Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5

Stress-activated transcription factors influence T-cell function in different physiopathologic contexts. NFAT5, a relative of nuclear factor κB and the calcineurin-activated NFATc transcription factors, protects mammalian cells from hyperosmotic stress caused by the elevation of extracellular sodium...

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Detalles Bibliográficos
Autores principales: Alberdi, Maria, Iglesias, Marcos, Tejedor, Sonia, Merino, Ramón, López-Rodríguez, Cristina, Aramburu, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215110/
https://www.ncbi.nlm.nih.gov/pubmed/27479742
http://dx.doi.org/10.1038/icb.2016.69