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Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5
Stress-activated transcription factors influence T-cell function in different physiopathologic contexts. NFAT5, a relative of nuclear factor κB and the calcineurin-activated NFATc transcription factors, protects mammalian cells from hyperosmotic stress caused by the elevation of extracellular sodium...
Autores principales: | Alberdi, Maria, Iglesias, Marcos, Tejedor, Sonia, Merino, Ramón, López-Rodríguez, Cristina, Aramburu, Jose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215110/ https://www.ncbi.nlm.nih.gov/pubmed/27479742 http://dx.doi.org/10.1038/icb.2016.69 |
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