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Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism

AIM: To evaluate the effects of the non-selective, non-steroidal anti-inflammatory drug (NSAID) acetylsalicylic acid (ASA), on ex vivo embryonic kidney growth and development. METHODS: Pairs of fetal mouse kidneys at embryonic day 12.5 were cultured ex vivo in increasing concentrations of ASA (0.04-...

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Detalles Bibliográficos
Autores principales: Welham, Simon J M, Sparrow, Alexander J, Gardner, David S, Elmes, Matthew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215205/
https://www.ncbi.nlm.nih.gov/pubmed/28101448
http://dx.doi.org/10.5527/wjn.v6.i1.21