Deficiency of the adaptor protein SLy1 results in a natural killer cell ribosomopathy affecting tumor clearance

Individuals with robust natural killer (NK) cell function incur lower rates of malignancies. To expand our understanding of genetic factors contributing to this phenomenon, we analyzed NK cells from cancer resistant and susceptible strains of mice. We identified a correlation between NK levels of th...

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Detalles Bibliográficos
Autores principales: Arefanian, Saeed, Schäll, Daniel, Chang, Stephanie, Ghasemi, Reza, Higashikubo, Ryuji, Zheleznyak, Alex, Guo, Yizhan, Yu, Jinsheng, Asgharian, Hosseinali, Li, Wenjun, Gelman, Andrew E., Kreisel, Daniel, French, Anthony R., Zaher, Hani, Plougastel-Douglas, Beatrice, Maggi, Leonard, Yokoyama, Wayne, Beer-Hammer, Sandra, Krupnick, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215235/
https://www.ncbi.nlm.nih.gov/pubmed/28123874
http://dx.doi.org/10.1080/2162402X.2016.1238543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215235/
https://www.ncbi.nlm.nih.gov/pubmed/28123874
http://dx.doi.org/10.1080/2162402X.2016.1238543

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