Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion

Gene conversions resulting from meiotic recombination are critical in shaping genome diversification and evolution. How the extent of gene conversions is regulated is unknown. Here we show that the budding yeast mismatch repair related MutLβ complex, Mlh1-Mlh2, specifically interacts with the conser...

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Detalles Bibliográficos
Autores principales: Duroc, Yann, Kumar, Rajeev, Ranjha, Lepakshi, Adam, Céline, Guérois, Raphaël, Md Muntaz, Khan, Marsolier-Kergoat, Marie-Claude, Dingli, Florent, Laureau, Raphaëlle, Loew, Damarys, Llorente, Bertrand, Charbonnier, Jean-Baptiste, Cejka, Petr, Borde, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215242/
https://www.ncbi.nlm.nih.gov/pubmed/28051769
http://dx.doi.org/10.7554/eLife.21900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215242/
https://www.ncbi.nlm.nih.gov/pubmed/28051769
http://dx.doi.org/10.7554/eLife.21900

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