CD36/Sirtuin 1 Axis Impairment Contributes to Hepatic Steatosis in ACE2-Deficient Mice

Background and Aims. Angiotensin converting enzyme 2 (ACE2) is an important component of the renin-angiotensin system. Since angiotensin peptides have been shown to be involved in hepatic steatosis, we aimed to evaluate the hepatic lipid profile in ACE2-deficient (ACE2(−/y)) mice. Methods. Male C57B...

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Detalles Bibliográficos
Autores principales: Nunes-Souza, Valéria, Alenina, Natalia, Qadri, Fatimunnisa, Penninger, Josef M., Santos, Robson Augusto S., Bader, Michael, Rabelo, Luiza A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215286/
https://www.ncbi.nlm.nih.gov/pubmed/28101297
http://dx.doi.org/10.1155/2016/6487509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215286/
https://www.ncbi.nlm.nih.gov/pubmed/28101297
http://dx.doi.org/10.1155/2016/6487509

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