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Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins

Interferon-induced transmembrane proteins (IFITMs) can inhibit the cellular entry of several enveloped viruses, including simian immunodeficiency virus (SIV). The blockade of SIV by IFITMs is isolate specific, raising the question of which parameters impact sensitivity to IFITM. We show that the vir...

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Detalles Bibliográficos
Autores principales: Wrensch, Florian, Hoffmann, Markus, Gärtner, Sabine, Nehlmeier, Inga, Winkler, Michael, Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215347/
https://www.ncbi.nlm.nih.gov/pubmed/27807233
http://dx.doi.org/10.1128/JVI.01488-16