Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses

Head-to-head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrated that these viral vectors can mediate more potent protection against influenza virus infection in animal models. In most cases, Ad vaccines are engineered to be replication-defective (RD-...

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Detalles Bibliográficos
Autores principales: Crosby, Catherine M., Matchett, William E., Anguiano-Zarate, Stephanie S., Parks, Christopher A., Weaver, Eric A., Pease, Larry R., Webby, Richard J., Barry, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215357/
https://www.ncbi.nlm.nih.gov/pubmed/27807231
http://dx.doi.org/10.1128/JVI.00720-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215357/
https://www.ncbi.nlm.nih.gov/pubmed/27807231
http://dx.doi.org/10.1128/JVI.00720-16

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