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The Paradoxical Effects of Different Hepatitis C Viral Loads on Host DNA Damage and Repair Abilities

Hepatitis C virus (HCV)-induced hepatic stress is associated with increased oxidative DNA damage and has been implicated in hepatic inflammation. However, HCV infection and replication are uneven and vary among individual hepatocytes. To investigate the effect of the viral load on host DNA damage, w...

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Detalles Bibliográficos
Autores principales: Wang, Shu-Chi, Lai, Kuan-Ru, Li, Chia-Yang, Chiang, Chi-Shiun, Yu, Guann-Yi, Sakamoto, Naoya, Tu, Wen-Yu, Hsieh, Meng-Hsuan, Huang, Jee-Fu, Chuang, Wan-Long, Dai, Chia-Yen, Yu, Ming-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215444/
https://www.ncbi.nlm.nih.gov/pubmed/28052067
http://dx.doi.org/10.1371/journal.pone.0164281