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Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment

Exposure to hexavalent chromium [Cr(VI)] in drinking water was previously reported to increase oral tumor incidence in F344 rats. To investigate the mode of action for these tumors, transcriptomic profiles in oral mucosa samples of F344 rats and B6C3F1 mice were analyzed following exposure to 0.1–18...

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Detalles Bibliográficos
Autores principales: Thompson, Chad M., Rager, Julia E., Suh, Mina, Ring, Caroline L., Proctor, Deborah M., Haws, Laurie C., Fry, Rebecca C., Harris, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215477/
https://www.ncbi.nlm.nih.gov/pubmed/27859739
http://dx.doi.org/10.1002/em.22064