Cargando…

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment

Exposure to hexavalent chromium [Cr(VI)] in drinking water was previously reported to increase oral tumor incidence in F344 rats. To investigate the mode of action for these tumors, transcriptomic profiles in oral mucosa samples of F344 rats and B6C3F1 mice were analyzed following exposure to 0.1–18...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thompson, Chad M., Rager, Julia E., Suh, Mina, Ring, Caroline L., Proctor, Deborah M., Haws, Laurie C., Fry, Rebecca C., Harris, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215477/ https://www.ncbi.nlm.nih.gov/pubmed/27859739 http://dx.doi.org/10.1002/em.22064

Ejemplares similares

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure
por: Rager, Julia E., et al.
Publicado: (2017)

Assessment of Cr(VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis
por: Thompson, Chad M., et al.
Publicado: (2012)

Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action
por: Thompson, Chad M., et al.
Publicado: (2012)

Synchrotron-Based Imaging of Chromium and γ-H2AX Immunostaining in the Duodenum Following Repeated Exposure to Cr(VI) in Drinking Water
por: Thompson, Chad M., et al.
Publicado: (2015)

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium
por: Thompson, Chad M., et al.
Publicado: (2017)

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin‐of‐exposure values for hexavalent chromium
por: Thompson, Chad M., et al.
Publicado: (2017)

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans
por: Thompson, Chad M., et al.
Publicado: (2013)

Ectopic pancreatic acinar cell carcinoma in the thoracic cavity of F344 rat
por: Fujiwara, Chinatsu, et al.
Publicado: (2023)

A chronic oral reference dose for hexavalent chromium-induced intestinal cancer†
por: Thompson, Chad M, et al.
Publicado: (2014)

Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium
por: Thompson, Chad M., et al.
Publicado: (2011)

Chronic mesothelial reaction and toxicity of potassium octatitanate fibers in the pleural cavity in mice and F344 rats
por: Yokohira, Masanao, et al.
Publicado: (2016)

Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium
por: Thompson, Chad M., et al.
Publicado: (2011)

Carcinogenesis by Nitrosohydroxyethylurea and Nitrosomethoxyethylurea in F344 Rats
por: Lijinsky, William, et al.
Publicado: (1988)

The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms)
por: Maronpot, Robert R., et al.
Publicado: (2016)

Theophylline-induced mesenteric periarteritis in F344/N rats
por: Nyska, Abraham, et al.
Publicado: (1998)

Carcinogenicity of Captafol in F344/DuCrj Rats
por: Tamano, Seiko, et al.
Publicado: (1990)

Reevaluation and Classification of Duodenal Lesions in B6C3F1 Mice and F344 Rats from 4 Studies of Hexavalent Chromium in Drinking Water
por: Cullen, John M., et al.
Publicado: (2015)

Spontaneous Extraskeletal Osteosarcoma in the Stomach of an Aged F344 Rat
por: Okazaki, Shuzo, et al.
Publicado: (2010)

Toxicity of Nicotine by Repeated Intratracheal Instillation to F344 Rats
por: Yokohira, Masanao, et al.
Publicado: (2012)

Lack of Carcinogenicity of Quercetin in F344/DuCrj Rats
por: Ito, Nobuyuki, et al.
Publicado: (1989)

Spontaneous nephroblastoma with striated muscle differentiation in an F344 rat
por: Tanaka, Natsuki, et al.
Publicado: (2017)

Neuromuscular and vascular hamartoma of the small intestine in an F344 rat
por: Yamada, Takanori, et al.
Publicado: (2020)

Spontaneous adenolipoma of the mammary gland in the male F344 rat
por: Ide, Tetsuya, et al.
Publicado: (2021)

Ovarian neoplasms in F344 rats and B6C3F1 mice.
por: Alison, R H, et al.
Publicado: (1987)

Life Cycle Analysis of Kidney Gene Expression in Male F344 Rats
por: Kwekel, Joshua C., et al.
Publicado: (2013)

Liver Carcinogencsis by Methyl Carbamate in F344 Rats and Not in B6C3F1 Mice
por: Chan, Po C., et al.
Publicado: (1992)

Effects of chloroform and bromodichloromethane on DNA synthesis in male F344 rat kidney.
por: Lipsky, M M, et al.
Publicado: (1993)

Proliferative lesions of the exocrine pancreas in male F344/N rats.
por: Boorman, G A, et al.
Publicado: (1984)

Extraskeletal Osteosarcoma with Pulmonary Metastasis in a Female F344 Rat
por: Nagaike, Mika, et al.
Publicado: (2011)

Phenotypic Properties of Liver Tumors Induced by Dehydroepiandrosterone in F‐344 Rats
por: Rao, M. Sambasiva, et al.
Publicado: (1992)

Letter to the Editor Regarding Banu et al. (2018). Chromium Accumulation on Human Placental Oxidative Stress and Apoptosis
por: Thompson, Chad M, et al.
Publicado: (2018)

Sex differences in kidney gene expression during the life cycle of F344 rats
por: Kwekel, Joshua C, et al.
Publicado: (2013)

Mutations of the Apc gene in experimental colorectal carcinogenesis induced by azoxymethane in F344 rats.
por: De Filippo, C., et al.
Publicado: (1998)

Evaluation of Transcriptomic Responses in Livers of Mice Exposed to the Short-Chain PFAS Compound HFPO-DA
por: Heintz, Melissa M., et al.
Publicado: (2022)

Toxicity of inhaled methyl isocyanate in F344/N rats and B6C3F1 mice. I. Acute exposure and recovery studies.
por: Bucher, J R, et al.
Publicado: (1987)

Modest induction of phase 2 enzyme activity in the F-344 rat prostate
por: Jones, Sunita B, et al.
Publicado: (2006)

Chronic effects of dietary exposure to amosite asbestos and tremolite in F344 rats.
por: McConnell, E E, et al.
Publicado: (1983)

Thyroid Hormone Signalling Genes Are Regulated by Photoperiod in the Hypothalamus of F344 Rats
por: Ross, Alexander W., et al.
Publicado: (2011)

Effects of Benzo(a)pyrene on Intra-testicular Function in F-344 Rats
por: Archibong, Anthony E., et al.
Publicado: (2008)

Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats
por: Tago, Yoshiyuki, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_k5f1pshcaqtu0r8lmvbpnv16fb