Cyclooxygenase-2 regulates TGFβ-induced cancer stemness in triple-negative breast cancer

Triple negative breast cancer (TNBC), an aggressive subtype of breast cancer, display poor prognosis and exhibit resistance to conventional therapies, partly due to an enrichment in breast cancer stem cells (BCSCs). Here, we investigated the role of the cyclooxygenase-2 (COX-2), a downstream target...

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Detalles Bibliográficos
Autores principales: Tian, Jun, Hachim, Mahmood Y., Hachim, Ibrahim Y., Dai, Meiou, Lo, Chieh, Raffa, Fatmah Al, Ali, Suhad, Lebrun, Jean Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215509/
https://www.ncbi.nlm.nih.gov/pubmed/28054666
http://dx.doi.org/10.1038/srep40258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215509/
https://www.ncbi.nlm.nih.gov/pubmed/28054666
http://dx.doi.org/10.1038/srep40258

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