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Cyclooxygenase-2 regulates TGFβ-induced cancer stemness in triple-negative breast cancer
Triple negative breast cancer (TNBC), an aggressive subtype of breast cancer, display poor prognosis and exhibit resistance to conventional therapies, partly due to an enrichment in breast cancer stem cells (BCSCs). Here, we investigated the role of the cyclooxygenase-2 (COX-2), a downstream target...
Autores principales: | Tian, Jun, Hachim, Mahmood Y., Hachim, Ibrahim Y., Dai, Meiou, Lo, Chieh, Raffa, Fatmah Al, Ali, Suhad, Lebrun, Jean Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215509/ https://www.ncbi.nlm.nih.gov/pubmed/28054666 http://dx.doi.org/10.1038/srep40258 |
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